Nucific Reviews

( 74 reviews )

Nucific, found online at, is a health and wellness company who says that their aim is to provide customers with cutting edge products backed by science that help their bodies operate at an optimum level.   

How Does It Work?

According to their website, the creators of Nucific knew that people’s bodies operate at their best when people are able to get regular exercise and have access to a proper diet, full of vitamins and nutrients.

However, the reality of most people’s busy lives is that it is actually incredibly difficult to incorporate regular exercise and to eat a diet that provides all the best vitamins and nutrients you need. 

Because of this, Nucific knew that the second best option would be for people to have access to high quality supplements that could fill in the gaps in people’s nutritional needs.

This is why Nucific chose to use on the most “cutting-edge, pure ingredients,” because the purer the ingredients, the better your body will be able to absorb them. In addition, their products are always free from preservatives, antibiotics, synthetic fillers and food coloring.

Finally, this company promises that their products are always tested by third-party labs in order to ensure and verify the potency and purity of their products, so customers don’t have to worry about they are putting in their bodies. 

Cost & Price Plans

The cost of using this website and accessing any of their published information is completely free of charge.  Their products will vary in price depending on what you choose to purchase and in what volume.

The prices of each product will be clearly displayed before you make your purchase. However, shipping will be free for all orders which total more than $50.00.         

Refund Policy

This company states that their “confidence is so high” that customers will get results from their products, that all their products are backed by a 90 day money-back guarantee.

The guarantee says that customers who dissatisfied with their order for any reason are welcome to call their Customer Service team to receive return instructions and request their refund. 

Customer Service Contact Info

Customers who would like to contact Customer Service with any questions, concerns, or complaints can do so by phone at 888-679-5520 or by email at [email protected]


There are actually a few important issues and problems with this supplement provider at this time, and they all stem directly from the products they provide to their customers which at this point in time is actually only three: Bio X4, CL X3, and Nucific Digest. 

All three of these products are presented as supplements intended to help improve digestive health and wellness, when the reality is that each of these supplements also makes promises about appetite suppressing and weight loss effects.

In addition, Bio X4 actually includes some ingredients that are not recommended to be used without the express direction of a doctor. 

The reality is that if a customer is looking for a nutritional supplement that will actually provide them with the nutrients they missing from their day-to-day diet, Nucific is not the right place for them. They should look to other supplement retailers to meet these needs. 

Competitors and Alternatives?

Certainly there are many, many other companies that specialize in the manufacturing of supplements, vitamins, and other health products, including, Gundry MD, and others.   

If you have any experience with Nucific or their products, please leave your reviews below.

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Nucific Customer Reviews

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Health benefits
September 15, 2022

I am feeling much better. I have more energy. My intestinal track is working better & I am getting more nutrients from my food. I appreciate the helpful hints for proper diet. I also starting to loose weight. But the main that is that my overall health is better.

Thank you Dr. Lee

Very happy with Bio-X4
September 15, 2022
I had severe issues with my guts and digestion so I’ve been looking for non pharmaceutical means of helping to deal with my on going issues. My appetite and my digestive problems have significantly decreased since beginning to take the Bio-x4 daily with my meals.Thank you very much giving us options to deal with issues like these. I am extremely pleased with the product.

September 15, 2022
Not sure of the weight loss effect yet, but the probiotic has been great for my digestion.

Not to old to change!
September 15, 2022
I will be 80 years old in a couple of months so I wasn’t expecting a miracle but I am feeling better as far as digestion and energy go! I am much more aware of what I put in my mouth and am drinking more water. I have lost eight pounds in my first month on Bio-X4 but the feeling better is the best!

Good Stuff
September 14, 2022
This product is very effective in boosting my metabolism and decreasing my cravings.

September 13, 2022
With Bio-x4 I have seen less bloating and better digestion. My son’s girlfriend is also using it because she had her gallbladder removed earlier this year and wasn’t able to eat all the foods, she use too. With using bio-x4 she can eat a lot more of the foods she likes, not all but a lot more!

I feel better overall, more energy and improved digestion
September 11, 2022

I’ve been taking it for a month and I have more energy during the day. My digestive system is much better bc I move my bowels in the am either before I eat / drink my protein shake or right after. I use psyllium daily bc more cholesterol was borderline and it has brought it down. My appetite has changed and not craving sweets and sugar. I look at cakes and remember what they taste like but don’t crave them. I’m 69 years old in post menopause and have gained 10 extra pounds that I want to shed. I was always 10 pounds under the weight prescribed for my height 5’7” and now I’m at the top of the range. I have an estrogen pouch around my umbilicus making my waistline bigger. My goal is to be 140 again. So I’m hoping I’ll lose this 10-12 pounds with the next 2 or more bottles. Oh, I have to remind myself to eat bc I’m not hunger and eat smaller portions. I have a very clean gluten free healthy diet to begin with and hope this takes me to the next level!

Loving It!!!
September 11, 2022

Love the program

Bio-x4 has help me take my weight loss to the next level!!! My first month on bio-x4 I saw an instant increase in the amount of weight I was losing each week. Feel great and energized.

Nucific Bio-X4
September 10, 2022
I’ve been using this product for awhile now. It helps my digestive system and also gives me energy.

Weight loss and Gut health
September 9, 2022

I initially started using Nucific in 2016 to lose weight along with a Keto plan. It stopped my craving and I have gone from 170 lbs to 128 lbs. I eventually quit taking it in 2020.

Now in 2022 I started having horrible intestinal issues to the point I needed a adult pull up at night.

I'm 64 yrs old with a history of Gastric Bypass.

I have a gastro appointment in October which I'm cancelling. I decided to try Nucfic Bio4 for its probiotic benefits and after a few days I'm back to normal, drinking coffee and no longer need to wear anything at night for accidents.

I definitly recommend this product for weightloss and prebiotic gut health.

It really does curb cravings!
September 8, 2022
I’ve managed to lose 10 lbs even though I haven’t been able to get into the gym. Heck, I’m not even dieting properly!!

Goal Making:
September 8, 2022

I started taking BIO-X4 about a month ago and am pleased with my result so far. To date I have lost 13 pounds. I have less cravings and have been able to feel full with eating less . Reflux and belching has stopped and digestion is better after eating.

As I have gotten older I have found it harder to control my weight. I’d like to lose another 13 to 20 pounds to reach my weight goal. My energy levels are up and I am having more nights with restful sleep.

Stomach health
September 7, 2022
I've been using this product for approximately 6 weeks I have lost 5 lb. I have a lot of stomach issues and I noticed that I'm feeling a lot better. I'm not as Burpee or gassy.

Voracious eater!
September 6, 2022
Started using the product about 4 weeks ago and i have lost 10 lbs of the 75 pounds I need to lose. The one thing that is most important is the "craving of food " has subsided significantly. I do exercise regularly but I am a voracious eater and I never thought any product would be able to control my appetite. Not sure if this is psychologically driven? I will continue to use this product to see how things go. The holidays are coming so that will be a test of all tests!

Do not eat out of routine and over eat at the same time, you are what you eat
September 6, 2022
In today’s eat on the go eat what you want when you please and no routine is a batch of just what it is absurd. With proper sleep being number one, following a schedule in regards to the body type you have and not over what you want is in direct correlation with results, Biodynamics is what cues the animals in the natural order and the same definition is in the quality of the probiotics found in Bio-X4, so happy to find a professional probiotic that truly works with the same standards it claims

NathanFox September 06, 2022

Best review next too sliced bread

Energy is is really high!
September 3, 2022
Feeling really good after taking Bio-4X for about 30 days. Good energy and hunger seems curbed! Still crave sweets, but hopefully that will subside with a bit more time!

That you stand behind your product
September 2, 2022

I'm in my late 50 and I'm pretty active. My gut health is something I never took into consideration. But after reading your information and using your product for a solid month now I just feel better and weight loss is a bonus. Thank you.

A great weight loss probiotic & appetite/sugar controller
August 31, 2022

I have used Bio-X4 for several years now & the product is fabulous. It helps in reducing sugar cravings, bloating, and helps curb my appetite. I am in my menopause years & this probiotic/weight management pill has helped me to not gain weight in my stomach & actually helped me lose weight and have more energy too! Truly a superb product!

not as hungry
August 29, 2022
When taking biox4 at each meal. I don't have the bloating and gas. I also have not been as hungry and my portion sizes have gotten smaller. Weight has not dropped off yet but also have a lot of muscle from barn chores each night.

It Plain Works
August 25, 2022
My wife and I have been using Bio-X4 for a number of years now, occasionally trying other products by various companies, including other Nucific formulations. Most are serviceable, but none can match the way we feel when compared to Bio-X4. Our whole body feels better with Bio-X4 and so simple to take and forget about it. Capsule twice a day and feel like champs. When we try something else, within a week we, especially my wife, can tell the difference: the cramps and difficult bathroom trips, etc. She says we got get back to Bio-X4. We now have a subscription and very pleased. It just plain works.